PPIST16197

Protein Information
Protein_Chain A;C[auth B]
Protein_Sequence AGAGAGAGAGSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLHAPTS
Peptide Information
Peptide_Chain B[auth C];D
Peptide_Sequence AILHRLLQ
Peptide_Length 8
Non-standard residues No
Interaction Information
PDB_ID 7YMK
Method X-RAY DIFFRACTION
Resolution 2.25 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Discovery of novel covalent selective estrogen receptor degraders against endocrine-resistant breast cancer.
Release_Year 2023
PMID 38045063
DOI 10.1016/j.apsb.2023.05.005