PPIST16278

Protein Information
Protein_Chain A
Protein_Sequence SMLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSPGPS
Peptide Information
Peptide_Chain B[auth C]
Peptide_Sequence ARKRRRHPSGPPTA
Peptide_Length 14
Non-standard residues No
Interaction Information
PDB_ID 8AFR
Method X-RAY DIFFRACTION
Resolution 2.15 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Pose, duplicate, then elaborate: Steps towards increased affinity for inhibitors targeting the specificity surface of the Pim-1 kinase.
Release_Year 2023
PMID 36410167
DOI 10.1016/j.ejmech.2022.114914