PPIST16295

Protein Information
Protein_Chain A
Protein_Sequence AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYAAALEHHHHHH
Peptide Information
Peptide_Chain B
Peptide_Sequence YANPALPWAWXXLCGX
Peptide_Length 16
Non-standard residues Yes
Interaction Information
PDB_ID 8ALX
Method X-RAY DIFFRACTION
Resolution 1.10 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Structural and biological characterization of pAC65, a macrocyclic peptide that blocks PD-L1 with equivalent potency to the FDA-approved antibodies.
Release_Year 2023
PMID 37679783
DOI 10.1186/s12943-023-01853-4