PPIST16671

Protein Information
Protein_Chain A
Protein_Sequence MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPAFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIATADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDL
Peptide Information
Peptide_Chain B[auth D]
Peptide_Sequence VPEGHEYYRVREDGD
Peptide_Length 15
Non-standard residues No
Interaction Information
PDB_ID 8EXN
Method X-RAY DIFFRACTION
Resolution 2.15 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Structure guided studies of the interaction between PTP1B and JAK.
Release_Year 2023
PMID 37316570
DOI 10.1038/s42003-023-05020-9