PPIST16677

Protein Information
Protein_Chain A
Protein_Sequence MTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKE
Peptide Information
Peptide_Chain B
Peptide_Sequence SSVPTKLEVVAATPTSLLISWDAPAVTVVFYDITYGETGGNSPVQEFTVPGSKSTATISGLSPGVDYTITVYAKYLWYSGYSSPISINYRT
Peptide_Length 91
Non-standard residues No
Interaction Information
PDB_ID 8EZG
Method X-RAY DIFFRACTION
Resolution 2.52 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Exploring switch II pocket conformation of KRAS(G12D) with mutant-selective monobody inhibitors.
Release_Year 2023
PMID 37399416
DOI 10.1073/pnas.2302485120