PPIST16680

Protein Information
Protein_Chain A;C
Protein_Sequence GSMTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK
Peptide Information
Peptide_Chain B;D
Peptide_Sequence GSSSVPTKLEVVAATPTSLLVSWDAPAVTVVFYDITYGETGGNSPVQEFTVPGSKSTATISGLSPGVDYTITVYAKYLFWSGYSSPISINYRTEIDK
Peptide_Length 97
Non-standard residues No
Interaction Information
PDB_ID 8F0M
Method X-RAY DIFFRACTION
Resolution 2.44 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Exploring switch II pocket conformation of KRAS(G12D) with mutant-selective monobody inhibitors.
Release_Year 2023
PMID 37399416
DOI 10.1073/pnas.2302485120