PPIST16701

Protein Information
Protein_Chain A;B;C
Protein_Sequence MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPAFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHASAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIATADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHN
Peptide Information
Peptide_Chain D[auth E];E[auth F];F[auth G]
Peptide_Sequence VLPQDKEYYKVKEPGE
Peptide_Length 16
Non-standard residues No
Interaction Information
PDB_ID 8F88
Method X-RAY DIFFRACTION
Resolution 3.10 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Structure guided studies of the interaction between PTP1B and JAK.
Release_Year 2023
PMID 37316570
DOI 10.1038/s42003-023-05020-9