PPIST16765

Protein Information
Protein_Chain A;B
Protein_Sequence GSHMSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHS
Peptide Information
Peptide_Chain C[auth D];D[auth H]
Peptide_Sequence AXPX
Peptide_Length 4
Non-standard residues Yes
Interaction Information
PDB_ID 8GH7
Method X-RAY DIFFRACTION
Resolution 1.75 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Characterization of a Potent and Orally Bioavailable Lys-Covalent Inhibitor of Apoptosis Protein (IAP) Antagonist.
Release_Year 2023
PMID 37262387
DOI 10.1021/acs.jmedchem.3c00467