PPIST16772

Protein Information
Protein_Chain A
Protein_Sequence LPGEGTQVHPRAPLLQILKVAGAQEEVFTVKEVMHYLGQYIMMKQLYDKQRQHIVHCHDDPLGELLEVGSFSVKNPSPLYEMLKRNLVIL
Peptide Information
Peptide_Chain B
Peptide_Sequence XLTFXEYWAQLLAAAAAA
Peptide_Length 18
Non-standard residues Yes
Interaction Information
PDB_ID 8GJS
Method X-RAY DIFFRACTION
Resolution 1.75 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Discovery of Sulanemadlin (ALRN-6924), the First Cell-Permeating, Stabilized alpha-Helical Peptide in Clinical Development.
Release_Year 2023
PMID 37439511
DOI 10.1021/acs.jmedchem.3c00623