PPIST16906

Protein Information
Protein_Chain A
Protein_Sequence GSSGGSTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDG
Peptide Information
Peptide_Chain B[auth I]
Peptide_Sequence AIGGFGFLFLD
Peptide_Length 11
Non-standard residues No
Interaction Information
PDB_ID 8JJS
Method X-RAY DIFFRACTION
Resolution 1.53 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor.
Release_Year 2023
PMID 37463267
DOI 10.1021/jacs.3c03886