PPIST16916

Protein Information
Protein_Chain A
Protein_Sequence MGYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHQLGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK
Peptide Information
Peptide_Chain B[auth C]
Peptide_Sequence XEGFVXX
Peptide_Length 7
Non-standard residues Yes
Interaction Information
PDB_ID 8JUG
Method X-RAY DIFFRACTION
Resolution 1.30 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Structure-Based Optimization and Biological Evaluation of Potent and Selective MMP-7 Inhibitors for Kidney Fibrosis.
Release_Year 2023
PMID 37861435
DOI 10.1021/acs.jmedchem.3c01166