PPIST17080

Protein Information
Protein_Chain A;B
Protein_Sequence ERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSL
Peptide Information
Peptide_Chain C;D
Peptide_Sequence XVRHX
Peptide_Length 5
Non-standard residues Yes
Interaction Information
PDB_ID 8AB5
Method X-RAY DIFFRACTION
Resolution 2.40 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Extensive targeting of chemical space at the prime side of ketoamide inhibitors of rhomboid proteases by branched substituents empowers their selectivity and potency.
Release_Year 2024
PMID 38901105
DOI 10.1016/j.ejmech.2024.116606