PPIST17162

Protein Information
Protein_Chain A;B
Protein_Sequence TTSGALFPSLVPGSRGASNKYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNEYLNNPPMPGALGASGSSGHELSAL
Peptide Information
Peptide_Chain C;D
Peptide_Sequence MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLR
Peptide_Length 72
Non-standard residues No
Interaction Information
PDB_ID 8FTQ
Method X-RAY DIFFRACTION
Resolution 2.10 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins.
Release_Year 2024
PMID 38509117
DOI 10.1038/s41467-024-46644-7