PPIST17267

Protein Information
Protein_Chain A
Protein_Sequence MGYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHQLGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK
Peptide Information
Peptide_Chain B
Peptide_Sequence XEGXVX
Peptide_Length 6
Non-standard residues Yes
Interaction Information
PDB_ID 8K4Z
Method X-RAY DIFFRACTION
Resolution 1.70 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Discovery of TP0628103: A Highly Potent and Selective MMP-7 Inhibitor with Reduced OATP-Mediated Clearance Designed by Shifting Isoelectric Points.
Release_Year 2024
PMID 38214909
DOI 10.1021/acs.jmedchem.3c01967