PPIST17295

Protein Information
Protein_Chain A
Protein_Sequence MSYYHHHHHHDYDIPTTENLYFQGAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT
Peptide Information
Peptide_Chain B
Peptide_Sequence RRRAISETEENSDELSGERQRKRHKSDSISL
Peptide_Length 31
Non-standard residues No
Interaction Information
PDB_ID 8P0D
Method X-RAY DIFFRACTION
Resolution 1.31 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Characterizing the protein-protein interaction between MDM2 and 14-3-3 sigma ; proof of concept for small molecule stabilization.
Release_Year 2024
PMID 38237679
DOI 10.1016/j.jbc.2024.105651