PPIST17791

Protein Information
Protein_Chain B[auth H]/A[auth L]
Protein_Sequence QSEEESGGRLVTPETPLTLTCTASGIDLSKWPMTWVRQAPGKGLEWIGIIGRSGSTNYASWAKGRFTISKTSTTVDLKMTSPTTEDTATYFCARGGSYYDLWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS/QVLTQTASPVSAAVGNTVTITCQSSQSVWKNNDLSWYQQKLGQPPKLLIYYASTLASGVSSRFKASGSGTQFTLTISDVQCDDAGTYYCVGSYDCSSADCNAFGGGTKVVVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
Peptide Information
Peptide_Chain C[auth P]
Peptide_Sequence EHHPMTEEFKN
Peptide_Length 11
Non-standard residues No
Interaction Information
PDB_ID 8YHZ
Method X-RAY DIFFRACTION
Resolution 1.62 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Intra-channel bi-epitopic crosslinking unleashes ultrapotent antibodies targeting Na V 1.7 for pain alleviation.
Release_Year 2024
PMID 39461335
DOI 10.1016/j.xcrm.2024.101800