PPIST17942

Protein Information
Protein_Chain A
Protein_Sequence GQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
Peptide Information
Peptide_Chain B[auth D]
Peptide_Sequence DPASNLGLEDIIRKALMGSFDDK
Peptide_Length 23
Non-standard residues No
Interaction Information
PDB_ID 8FKD
Method X-RAY DIFFRACTION
Resolution 2.22 angstrom
Structure
Protein-peptide residue interaction
Residues
Acidic
Polar
Basic
Aliphatic
Aromatic
Interactions
HBond
WaterBridge
Hydrophobic
SaltBridge
PiStack
PiCation
Halogen
Metal
Interaction_xlsx Download interaction table (.xlsx)
Reference Information
Title Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states.
Release_Year 2025
PMID 40021712
DOI 10.1038/s41467-025-57325-4